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ALPHA-2-ANTIPLASMIN
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DeCS
Descriptor
English
:
alpha-2-Antiplasmin
Descriptor
Spanish
:
alfa 2-Antiplasmina
Descriptor
Portuguese
:
alfa 2-Antiplasmina
Synonyms
English
:
alpha 2-Plasmin Inhibitor
Tree Number:
D12.644.822.750.050
D12.644.861.050
D12.776.124.790.106.090
D12.776.377.715.085.090
D12.776.395.080
D12.776.645.750.050
D12.776.872.050
Definition
English
:
A member of the
serpin superfamily
found in
plasma
that inhibits the lysis of
fibrin
clots which are induced by
plasminogen
activator. It is a glycoprotein,
molecular weight
approximately 70,000 that migrates in the alpha 2 region in
immunoelectrophoresis
. It is the principal
plasmin
inactivator in blood, rapidly forming a very stable complex with
plasmin.
Pharmacological Action:
Antifibrinolytic Agents
Serine Proteinase Inhibitors
History Note
English
:
2010(1980)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
28329
Unique Identifier:
D000979
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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