Search on: CLAUDIN-4 
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Descriptor English:   Claudin-4 
Descriptor Spanish:   Claudina-4 
Descriptor Portuguese:   Claudina-4 
Synonyms English:   Claudin4  
Tree Number:   D12.776.543.984.200.400
Definition English:   A claudin subtype that takes part in maintaining the barrier-forming property of TIGHT JUNCTIONS. Claudin-4 is found associated with CLAUDIN-8 in the KIDNEY COLLECTING DUCT where it may play a role in paracellular chloride ion reabsorption. 
History Note English:   2013 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   54980 
Unique Identifier:   D062506 

Occurrence in VHL: 		 

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