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DRUG TOLERANCE
Descriptors Found:
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DeCS
Descriptor
English
:
Drug Tolerance
Descriptor
Spanish
:
Tolerancia a Medicamentos
Descriptor
Portuguese
:
Tolerāncia a Medicamentos
Tree Number:
G07.690.812.260
G07.700.680.260
Definition
English
:
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued
administration
. It should be differentiated from
DRUG RESISTANCE
wherein an organism,
disease
, or tissue fails to respond to the intended
effectiveness
of a chemical or drug. It should also be differentiated from
MAXIMUM TOLERATED DOSE
and
NO-OBSERVED-ADVERSE-EFFECT LEVEL.
Indexing Annotation
English
:
differentiate from
DRUG RESISTANCE
; not for tolerability ( = drug /adv eff): Manual 28.19
Allowable Qualifiers
English
:
EH
ethnology
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
4420
Unique Identifier:
D004361
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS