Pesquisa sobre: TRANSFORMING GROWTH FACTOR BETA1 
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Descritor Inglês:   Transforming Growth Factor beta1 
Descritor Espanhol:   Factor de Crecimiento Transformador beta1 
Descritor Português:   Fator de Crescimento Transformador beta1 
Sinônimos Inglês:   TGF-beta1  
Categoria:   D12.644.276.374.687.100
D12.644.276.954.800.720.100
D12.644.276.963.720.100
D12.776.467.374.687.100
D12.776.467.942.800.720.100
D12.776.467.960.720.100
D23.529.374.687.100
D23.529.942.800.720.100
D23.529.960.720.100
Definição Inglês:   A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME. 
Combinados Inglês:   Transforming Growth Factor beta1/deficiency use Camurati-Engelmann Syndrome
 
Nota Histórica Inglês:   2007(1992) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   52285 
Identificador Único:   D053773 

Ocorrência na BVS:
 

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