Pesquisa sobre: PHOSPHOFRUCTOKINASE-2 
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Descritor Inglês:   Phosphofructokinase-2 
Descritor Espanhol:   Fosfofructoquinasa-2 
Descritor Português:   Fosfofrutoquinase-2 
Sinônimos Inglês:   6-Phosphofructo-2-kinase
6-Phosphofructo-2-kinase-fructose-2,6-bisphosphatase
Fructose-2,6-bisphosphatase  
Categoria:   D08.811.277.352.650.622
D08.811.641.843
D08.811.913.696.620.225.850.750
Definição Inglês:   An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate. 
Relacionados Inglês:   Phosphofructokinase-1
 
Nota Histórica Inglês:   2002; for 6-PHOSPHOFRUCTO-2-KINASE use PHOSPHOTRANSFERASES (NM) 1993-2001, use PHOSPHOTRANSFERASES, ATP (NM) 1981-1993; for FRUCTOSE-2,6-BISPHOSPATASE use PHOSPHORIC MONOESTER HYDROLASES (NM) 1983-2001; for 6-PHOSPHOFRUCTO-2-KINASE-FRUCTOSE-2,6-BISPHOSPHATASE use FRUCTOSE-BISPHOSPHATASE (NM) 1990-2001, use MULTIENZYME COMPLEXES (NM) 1990-2001, use PHOSPHOFRUCTOKINASE-1 (NM) 1990-2001 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   36081 
Identificador Único:   D025481 

Ocorrência na BVS:
 

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