Pesquisa sobre:
MATRIX METALLOPROTEINASE 14
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Matrix Metalloproteinase 14
Descritor
Espanhol
:
Metaloproteinasa 14 de la Matriz
Descritor
Português
:
Metaloproteinase 14 da Matriz
Categoria:
D08.811.277.656.300.480.525.300.500
D08.811.277.656.675.374.525.300.500
Definição
Inglês
:
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of
PROPROTEIN CONVERTASES
such as FURIN.
Matrix metalloproteinase 14
plays a direct role in the cleavage of
proteins
in the pericellular
environment
. In addition, it can function indirectly by enzymatically activating the proprotein form of
MATRIX METALLOPROTEINASE 15.
Combinados
Inglês
:
Matrix Metalloproteinase 14
/
antagonists & inhibitors
use
Matrix Metalloproteinase Inhibitors
Nota Histórica
Inglês
:
2007(1994)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
52233
Identificador Único:
D053511
Ocorrência na BVS
:
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