Pesquisa sobre:
CASPASE 8
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Caspase 8
Descritor
Espanhol
:
Caspasa 8
Descritor
Português
:
Caspase 8
Categoria:
D08.811.277.656.262.500.126.550.800
D08.811.277.656.300.200.126.550.800
D12.644.360.075.405.550.800
D12.776.476.075.405.550.800
Definição
Inglês
:
A long pro-domain caspase that contains a death effector domain in its pro-domain region.
Caspase 8
plays a role in
APOPTOSIS
by cleaving and activating EFFECTOR
CASPASES
. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with
DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS
.
Combinados
Inglês
:
Caspase 8
/
antagonists & inhibitors
use
Caspase Inhibitors
Caspase 8
/
deficiency
use
Alstrom Syndrome
Relacionados
Inglês
:
Autoimmune Lymphoproliferative Syndrome
Nota Histórica
Inglês
:
2007(2000)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
52227
Identificador Único:
D053181
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
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