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VIGABATRIN
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DeCS
Descriptor
English
:
Vigabatrin
Descriptor
Spanish
:
Vigabatrin
Descriptor
Portuguese
:
Vigabatrina
Synonyms
English
:
gamma-Vinyl-gamma-Aminobutyric Acid
Tree Number:
D02.241.081.114.500.350.900
D12.125.190.350.900
Definition
English
:
An analogue of
GAMMA-AMINOBUTYRIC ACID
. It is an irreversible inhibitor of
4-AMINOBUTYRATE TRANSAMINASE
, the enzyme responsible for the catabolism of
GAMMA-AMINOBUTYRIC ACID
. (From Martindale The Extra Pharmacopoeia, 31st ed)
Pharmacological Action:
Anticonvulsants
Enzyme Inhibitors
GABA Agents
History Note
English
:
2000; use VIGABATRIN 1977-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
34388
Unique Identifier:
D020888
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS