Search on: VEGFR-2 
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Descriptor English:   Vascular Endothelial Growth Factor Receptor-2 
Descriptor Spanish:   Receptor 2 de Factores de Crecimiento Endotelial Vascular 
Descriptor Portuguese:   Receptor 2 de Fatores de Crescimento do Endotélio Vascular 
Synonyms English:   VEGFR-2  
Tree Number:   D08.811.913.696.620.682.725.400.950.200
D12.776.543.750.060.750.200
D12.776.543.750.750.400.910.200
Definition English:   A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their precursors. VEGFR-2 is important for vascular and hematopoietic development, and mediates almost all endothelial cell responses to VEGF. 
History Note English:   2003; for FETAL LIVER KINASE-1, KDR TYROSINE KINASE, FLK-1 RECEPTOR TYROSINE KINASE & FLK-1 PROTEIN use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR 1993-2002; for VEGFR-2 use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR 1996-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37359 
Unique Identifier:   D040301 

Occurrence in VHL:
 

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