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PODOCYTES
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DeCS
Descriptor
English
:
Podocytes
Descriptor
Spanish
:
Podocitos
Descriptor
Portuguese
:
Podócitos
Synonyms
English
:
Visceral Epithelial Cells, Glomerular
Tree Number:
A05.810.453.324.359.372.650
A05.810.453.736.520.720
A11.436.720
Definition
English
:
Highly differentiated
epithelial cells
of the visceral layer of
BOWMAN CAPSULE
of the
KIDNEY
. They are composed of a
cell body
with major
CELL SURFACE EXTENSIONS
and secondary fingerlike extensions called pedicels. They enwrap the
KIDNEY GLOMERULUS
capillaries
with their
cell surface extensions
forming a
filtration
structure. The pedicels of neighboring
podocytes
interdigitate with each other leaving between them
filtration
slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit
diaphragm
, and provide the last barrier to protein loss in the
KIDNEY.
History Note
English
:
2006
Allowable Qualifiers
English
:
CH
chemistry
CL
classification
CY
cytology
DE
drug effects
EN
enzymology
IM
immunology
ME
metabolism
MI
microbiology
PS
parasitology
PA
pathology
PH
physiology
RE
radiation effects
RA
radiography
RI
radionuclide imaging
SE
secretion
TR
transplantation
US
ultrasonography
UL
ultrastructure
VI
virology
Record Number:
50371
Unique Identifier:
D050199
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS