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TAU PROTEINS
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DeCS
Descriptor
English
:
tau Proteins
Descriptor
Spanish
:
Proteínas tau
Descriptor
Portuguese
:
Proteínas tau
Tree Number:
D12.776.220.600.450.510
D12.776.641.560.510
Definition
English
:
Microtubule-associated proteins
that are mainly expressed in
neurons
.
Tau proteins
constitute several isoforms and play an important role in the assembly of
tubulin
monomers into
microtubules
and in maintaining the
cytoskeleton
and
axonal transport
. Aggregation of specific sets of
tau proteins
in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (
NEUROFIBRILLARY TANGLES
;
NEUROPIL THREADS
) in numerous neurodegenerative disorders (
ALZHEIMER DISEASE
;
TAUOPATHIES
).
See Related
English
:
Tauopathies
History Note
English
:
1992; use TAU (NM) 1977-91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30290
Unique Identifier:
D016875
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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