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T4 ANTIGENS, T-CELL
Descriptors Found:
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DeCS
Descriptor
English
:
Antigens, CD4
Descriptor
Spanish
:
Antígenos CD4
Descriptor
Portuguese
:
Antígenos CD4
Synonyms
English
:
CD4 Antigens
CD4 Molecule
T4 Antigens, T-Cell
CD4 Receptors
Receptors, CD4
Tree Number:
D12.776.543.750.705.852.420.810.500
D12.776.543.750.925.700.025
D23.050.301.264.035.104
D23.050.301.264.894.100
D23.101.100.110.104
D23.101.100.894.100
Definition
English
:
55-kDa
antigens
found on HELPER-INDUCER
T-LYMPHOCYTES
and on a variety of other immune cell types. CD4
antigens
are members of the immunoglobulin supergene
family
and are implicated as associative recognition
elements
in
MAJOR HISTOCOMPATIBILITY COMPLEX
class II-restricted immune responses. On
T-lymphocytes
they define the helper/inducer subset. CD4
antigens
also serve as
INTERLEUKIN-15
receptors and bind to the HIV receptors, binding directly to the
HIV ENVELOPE PROTEIN GP120.
Indexing Annotation
English
:
for hematodermic CD4/CD56 neoplasm use
LYMPHOMA
, NON-HODGKIN
See Related
English
:
CD4-CD8 Ratio
HIV Envelope Protein gp120
History Note
English
:
90; was CD4 ANTIGENS see ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
24525
Unique Identifier:
D015704
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS