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SMALL GTPASES
Descriptors Found:
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DeCS
Descriptor
English
:
Monomeric GTP-Binding Proteins
Descriptor
Spanish
:
Proteínas de Unión al GTP Monoméricas
Descriptor
Portuguese
:
Proteínas Monoméricas de Ligação ao GTP
Synonyms
English
:
ras-Related GTPases
G-Proteins, Monomeric
GTP-Binding Proteins, Monomeric
Monomeric G-Proteins
Small G-Proteins
Small GTPases
Tree Number:
D08.811.277.040.330.300.400
D12.644.360.525
D12.776.157.325.515
D12.776.476.525
Definition
English
:
A class of monomeric, low
molecular weight
(20-25 kDa)
GTP-binding proteins
that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of
GTPase activators
, GDP dissociation inhibitors, and
guanine nucleotide exchange factors
. This enzyme was formerly listed as EC 3.6.1.47
History Note
English
:
2000
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34413
Unique Identifier:
D020559
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS