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SHIGA TOXINS
Descriptors Found:
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DeCS
Descriptor
English
:
Shiga Toxins
Descriptor
Spanish
:
Toxinas Shiga
Descriptor
Portuguese
:
Toxinas Shiga
Synonyms
English
:
Vero Toxin
Vero Toxins
Tree Number:
D08.811.277.450.430.700.750.750
D23.946.123.794
D23.946.330.575
Definition
English
:
A class of toxins that inhibit protein synthesis by blocking the interaction of
ribosomal RNA
; (RNA, RIBOSOMAL) with
PEPTIDE ELONGATION FACTORS
. They include
SHIGA TOXIN
which is produced by
SHIGELLA DYSENTERIAE
and a variety of shiga-like toxins that are produced by pathologic strains of
ESCHERICHIA COLI
such as
ESCHERICHIA COLI O157.
Indexing Annotation
English
:
SHIGA TOXIN
is also available
Pharmacological Action:
Protein Synthesis Inhibitors
See Related
English
:
Dysentery
History Note
English
:
2001; for VERO CYTOTOXIN, VERO CELL CYTOTOXIN, VERO TOXIN & VERO TOXIN use SHIGA-LIKE TOXIN I (NM) 1980-2000
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
35357
Unique Identifier:
D022603
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS