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MAPK-ERK KINASES
Descriptors Found:
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DeCS
Descriptor
English
:
Mitogen-Activated Protein Kinase Kinases
Descriptor
Spanish
:
Quinasas de Proteína Quinasa Activadas por Mitógenos
Descriptor
Portuguese
:
Quinases de Proteína Quinase Ativadas por Mitógeno
Synonyms
English
:
MAP Kinase Kinases
MAPK Kinases
MAPK-ERK Kinases
MAPKKs
MEKs
Tree Number:
D08.811.913.696.620.682.700.565
D08.811.913.696.620.682.725.200
D12.644.360.440
D12.776.476.440
Definition
English
:
A serine-threonine protein kinase
family
whose members are components in protein kinase cascades activated by diverse stimuli. These MAPK kinases phosphorylate
MITOGEN-ACTIVATED PROTEIN KINASES
and are themselves phosphorylated by
MAP KINASE KINASE KINASES
. JNK kinases (also known as SAPK kinases) are a subfamily.
See Related
English
:
MAP Kinase Signaling System
History Note
English
:
2000; for MAP-ERK KINASE use MEK1 PROTEIN (NM) 1992-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34449
Unique Identifier:
D020929
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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