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LEUKOCYTE L1 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Leukocyte L1 Antigen Complex
Descriptor
Spanish
:
Complejo de Antígeno L1 de Leucocito
Descriptor
Portuguese
:
Complexo Antígeno L1 Leucocitário
Synonyms
English
:
L1 Antigen
Leukocyte L1 Protein
Tree Number:
D12.776.157.125.750.500
D12.776.641.655.500
D23.050.301.562
Definition
English
:
A member of the S-100 protein
family
that is present at high levels in the blood and
interstitial fluid
in several infectious, inflammatory, and malignant disorders, including
rheumatoid arthritis
, inflammatory bowel
disease
, and
cystic fibrosis
. It is a complex of a light chain (
CALGRANULIN A
) and a heavy chain (
CALGRANULIN B
). L1 binds
calcium
through an EF-hand motif, and has been shown to possess antimicrobial activity.
History Note
English
:
2003; use LEUKOCYTE L1 ANTIGEN COMPLEX (NM) 1984-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
37387
Unique Identifier:
D039841
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS