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LAK CELLS
Descriptors Found:
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DeCS
Descriptor
English
:
Killer Cells, Lymphokine-Activated
Descriptor
Spanish
:
Células Asesinas Activadas por Linfoquinas
Descriptor
Portuguese
:
Células Matadoras Ativadas por Linfocina
Synonyms
English
:
LAK Cells
Lymphokine-Activated Killer Cells
Tree Number:
A11.118.637.555.283.500
A11.118.637.555.567.537.500
A15.145.229.637.555.283.500
A15.145.229.637.555.567.537.500
A15.382.490.555.283.500
A15.382.490.555.567.537.500
Definition
English
:
Cytolytic
lymphocytes
with the unique capacity of killing natural killer (NK)-resistant fresh tumor cells. They are INTERLEUKIN-2-activated NK cells that have no
MAJOR HISTOCOMPATIBILITY COMPLEX
restriction or need for antigen stimulation. LAK cells are used for ADOPTIVE
IMMUNOTHERAPY
in cancer
patients.
Indexing Annotation
English
:
if subpopulations are discussed, coordinate IM with
LYMPHOCYTE SUBSETS
(IM)
See Related
English
:
Immunotherapy, Adoptive
Interleukin-2
History Note
English
:
90
Allowable Qualifiers
English
:
CH
chemistry
CL
classification
CY
cytology
DE
drug effects
EN
enzymology
IM
immunology
ME
metabolism
MI
microbiology
PS
parasitology
PA
pathology
PH
physiology
RE
radiation effects
RA
radiography
RI
radionuclide imaging
SE
secretion
TR
transplantation
US
ultrasonography
UL
ultrastructure
VI
virology
Record Number:
24762
Unique Identifier:
D015979
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS