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G-PROTEIN REGULATING FACTORS
Descriptors Found:
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DeCS
Descriptor
English
:
GTP-Binding Protein Regulators
Descriptor
Spanish
:
Reguladores de Proteínas de Unión al GTP
Descriptor
Portuguese
:
Reguladores de Proteínas de Ligação ao GTP
Synonyms
English
:
G-Protein Regulating Factors
G-Protein Signaling Regulators
Regulators, G-Protein Signaling
Tree Number:
D12.644.360.325
D12.776.402
D12.776.476.325
Definition
English
:
Proteins
that regulate the signaling activity of
GTP-BINDING PROTEINS
. They are divided into three categories depending upon whether they stimulate GTPase activity (
GTPASE-ACTIVATING PROTEINS
), inhibit release of GDP; (
GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS
); or exchange GTP for GDP; (
GUANINE NUCLEOTIDE EXCHANGE FACTORS
).
Indexing Annotation
English
:
Do not confuse with
RGS proteins
; DF: GTP BINDING PROTEIN REG
History Note
English
:
2000
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34481
Unique Identifier:
D020555
Occurrence in VHL
:
Similar:
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CID-10
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