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FOLATE POLYGLUTAMATES
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DeCS
Descriptor
English
:
Pteroylpolyglutamic Acids
Descriptor
Spanish
:
Ácidos Pteroilpoliglutámicos
Descriptor
Portuguese
:
Ácidos Pteroilpoliglutâmicos
Synonyms
English
:
Folate Polyglutamates
Polyglutamate Folates
Tree Number:
D03.438.733.631.400.600
Definition
English
:
Derivatives of
folic acid
(pteroylglutamic acid). In gamma-glutamyl linkage they are found in many
tissues
. They are converted to
folic acid
by the action of pteroylpolyglutamate hydrolase or synthesized from
folic acid
by the action of folate polyglutamate synthetase. Synthetic
pteroylpolyglutamic acids
, which are in alpha-glutamyl linkage, are active in
bacterial growth
assays.
Indexing Annotation
English
:
deficiency: coordinate
PTEROYLPOLYGLUTAMIC ACIDS
/defic (IM) with
FOLIC ACID DEFICIENCY
(IM)
Pharmacological Action:
Vitamin B Complex
History Note
English
:
91(79); was see under FOLIC ACID 1979-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
27777
Unique Identifier:
D011624
Occurrence in VHL
:
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CID-10
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