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EPH RECEPTOR TYROSINE KINASE
Descriptors Found:
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DeCS
Descriptor
English
:
Receptors, Eph Family
Descriptor
Spanish
:
Receptores de la Familia Eph
Descriptor
Portuguese
:
Receptores da Família Eph
Synonyms
English
:
Eph Family Receptors
Eph Receptor Tyrosine Kinase
Tree Number:
D08.811.913.696.620.682.725.400.850
D12.776.543.750.060.500
Definition
English
:
A large
family
of
receptor protein-tyrosine kinases
that are structurally-related. The name of this
family
of
proteins
derives from original protein Eph (now called the
EPHA1 RECEPTOR
), which was named after the
cell line
it was first discovered in: Erythropoietin-Producing human Hepatocellular
carcinoma
cell line
. Members of this
family
have been implicated in regulation of cell-cell interactions involved in
nervous system
patterning and development.
History Note
English
:
2003; use RECEPTORS, EPH FAMILY (NM) 1999-2002, for EPH RECEPTOR TYROSINE KINASE use EPHA1 RECEPTOR (NM) 1999-2002;
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
37343
Unique Identifier:
D036081
Occurrence in VHL
:
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