Search on: DIHYDROPTERIDINE REDUCTASE 
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Descriptor English:   Dihydropteridine Reductase 
Descriptor Spanish:   Dihidropteridina Reductasa 
Descriptor Portuguese:   Di-Hidropteridina Redutase 
Tree Number:   D08.811.682.662.162
D08.811.682.662.582.361
Definition English:   An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7. 
Entry Combination - descr/qualif English:   Dihydropteridine Reductase/deficiency use Phenylketonurias
 
History Note English:   91(75); was see under NADH, NADPH OXIDOREDUCTASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   4133 
Unique Identifier:   D004093 

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