Search on:
BREAST CANCER 2 GENE PRODUCT
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
BRCA2 Protein
Descriptor
Spanish
:
Proteína BRCA2
Descriptor
Portuguese
:
Proteína BRCA2
Synonyms
English
:
Breast Cancer 2 Gene Product
Fanconi Anemia Complementation Group D1 Protein
Tree Number:
D12.776.313.249
D12.776.624.776.101
D12.776.660.105
Definition
English
:
A large, nuclear protein, encoded by the
BRCA2 gene
(GENE, BRCA2). Mutations in this gene predispose
humans
to
breast
and ovarian cancer. The
BRCA2 protein
is an essential component of
DNA repair
pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)
See Related
English
:
Hereditary Breast and Ovarian Cancer Syndrome
History Note
English
:
2002; use BRCA2 PROTEIN (NM) 1995-2001
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
36228
Unique Identifier:
D024682
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS